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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 21.21
Human Site: S297 Identified Species: 29.17
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 S297 Q T S F Q L L S A S A C P E Y
Chimpanzee Pan troglodytes XP_526227 1093 122795 S297 Q T S F Q L L S A S A C P E Y
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 S296 Q T S F Q L L S A S A C P E Y
Dog Lupus familis XP_533766 1089 122761 S295 S F Q L L S A S A C P E Y N R
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 S295 S F Q L L S A S A C P E Y S R
Rat Rattus norvegicus NP_446123 1093 121882 S296 S F Q L L S A S A C P E Y G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 S303 Q T S F Q L L S A S A C P E Y
Chicken Gallus gallus O42184 1433 161009 L395 E I E Q E L A L V R D G H D R
Frog Xenopus laevis Q5PQ23 649 75475
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 S323 Q G S F Q L L S A S T C S D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 S247 D Q S Y S S T S S D I E I I S
Honey Bee Apis mellifera XP_394037 1326 150590 D336 P I D Q K N S D S S S I L D R
Nematode Worm Caenorhab. elegans P02566 1966 225108 S928 E A Q Q K D A S K Q L S E L N
Sea Urchin Strong. purpuratus XP_785821 1176 131318 E302 S T S T G T V E A D E K E G E
Poplar Tree Populus trichocarpa XP_002303293 975 109171 L290 E M V H E F S L S D A S P L D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 P271 H V N R I E S P V A H P S L I
Baker's Yeast Sacchar. cerevisiae P47166 707 81153 N22 T K K G R K K N K R S T S N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 100 100 13.3 N.A. 13.3 13.3 N.A. 100 6.6 0 66.6 N.A. 13.3 6.6 6.6 20
P-Site Similarity: 100 100 100 13.3 N.A. 13.3 13.3 N.A. 100 26.6 0 80 N.A. 26.6 33.3 20 26.6
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 13.3 N.A. N.A. 0 0 N.A.
P-Site Similarity: 33.3 N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 0 0 0 30 0 53 6 30 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 18 0 30 0 0 0 % C
% Asp: 6 0 6 0 0 6 0 6 0 18 6 0 0 18 6 % D
% Glu: 18 0 6 0 12 6 0 6 0 0 6 24 12 24 6 % E
% Phe: 0 18 0 30 0 6 0 0 0 0 0 0 0 0 6 % F
% Gly: 0 6 0 6 6 0 0 0 0 0 0 6 0 12 0 % G
% His: 6 0 0 6 0 0 0 0 0 0 6 0 6 0 0 % H
% Ile: 0 12 0 0 6 0 0 0 0 0 6 6 6 6 6 % I
% Lys: 0 6 6 0 12 6 6 0 12 0 0 6 0 0 0 % K
% Leu: 0 0 0 18 18 36 30 12 0 0 6 0 6 18 6 % L
% Met: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 6 0 0 6 0 6 0 0 0 0 0 12 6 % N
% Pro: 6 0 0 0 0 0 0 6 0 0 18 6 30 0 0 % P
% Gln: 30 6 24 18 30 0 0 0 0 6 0 0 0 0 0 % Q
% Arg: 0 0 0 6 6 0 0 0 0 12 0 0 0 0 30 % R
% Ser: 24 0 42 0 6 24 18 59 18 36 12 12 18 6 6 % S
% Thr: 6 30 0 6 0 6 6 0 0 0 6 6 0 0 0 % T
% Val: 0 6 6 0 0 0 6 0 12 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 0 0 0 0 0 0 18 0 24 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _